Wound treatment and pain management: A stressful time

Kyoichi Matsuzaki, Dominic Upton

Research output: Contribution to journalArticlepeer-review


This review and case study report considers the evidence to indicate that the progress of wound healing is negatively affected by the presence of stressors and in circumstances where patients are in painIt considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus on guidance for clinical practiceIt is appreciated that although the literature has examined these issues in the management of acute wounds, demonstrating that psychological stress can have detrimental effects on the wound-healing process, the evidence to support this link in relation to chronic wounds is limitedThe review considers evidence indicating that punch biopsy wounds heal more slowly in subjects under stress on account of caring for family members with long-term illnesses and also considers briefly the relationship between cortisol secretion in response to stress and the consequent influences on cytokine levels and the wound-healing process.

Original languageEnglish
Pages (from-to)638-644
Number of pages7
JournalInternational Wound Journal
Issue number6
Early online date21 Aug 2012
Publication statusPublished - 1 Dec 2013
Externally publishedYes


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